NEUROTOL is contraindicated in patients with:
Congestive heart failure as it increases extracellular fluid thereby increasing the load on already decompensated heart
- Pulmonary congestion
- Electroluyte Depletion
- Severe Dehydration
- Well established Anuria
- Acute intracranial bleeding except during craniotomy.
- Progressive renal damage
PRECAUTIONS
The cardiovascular status of the patient should be carefully evaluated before rapidly administering NEUROTOL since with mannitol sudden expansion of extracellular fluid may lead to culminating congestive heart failure.
NEUROTOL should not be administered simultaneously with blood as it may cause pseudo agglutination due to presence of mannitol in the preparation. If at all it is essential that blood is to be given simuyltaneusly , atleast 20mEq of sodium chloride should be added per litre to the preparation Rapid infusion of NEUROTOL should be carefully monitored as glycerol is not to be infused rapidly. There are no clinical evidences of use of NEUROTOL in pregnant or lactating women The dosing in elderly requires careful monitoring but no dose adjustment may be required.
NEUROTOL should not be administered simultaneously with blood as it may cause pseudo agglutination due to presence of mannitol in the preparation. If at all it is essential that blood is to be given simuyltaneusly , atleast 20mEq of sodium chloride should be added per litre to the preparation Rapid infusion of NEUROTOL should be carefully monitored as glycerol is not to be infused rapidly. There are no clinical evidences of use of NEUROTOL in pregnant or lactating women The dosing in elderly requires careful monitoring but no dose adjustment may be required.
DOSAGE AND ADMINISTRATION:
- cerebral oedema: 50 gm to 200 gm (250-1000 ml) over a period of 24 hrs adjusted to maintain urinary output of 30 to 50 ml per hour.
- Glaucoma: 1.5 – 2 g per kg body weight over period of 30 – 60 minutes.
RATE OF ADMINISTRATION :
Cerebral oedema: rate of infusion should not exceed 40 drops per minute. Other indications: Rate of infusion may be adjusted according to the patients need
PRESENTATION
NEUROTOL is available with single cartons 100 ml and 350 ml glass bottles.
Neurotol Slider
